• HOME
  • 森下竜一 寄附講座教授
  • 概要・沿革
  • グループ紹介
  • 核酸医薬グループ
  • 認知症グループ
  • 心・血管グループ
  • 健康発達医学グループ
  • 免疫・脳血管・神経グループ
  • 共同研究グループ
  • 院生、研究生、修士大募集
  • 技術補佐員等募集
  • CGT写真館
  • MORISHITA AWARD
  • 臨床試験
  • 外来診察担当表
  • お知らせ
  • 関連リンク
  • お問合せ
Home ＞ グループ紹介 ＞ 共同研究グループ

グループ紹介

共同研究グループ
  Gリーダー 研究テーマ 主な論文

主な論文

青木元邦 勝谷友宏 里 直行 谷山義明 橋弥尚孝 日比野佐和子
東 純哉 牧野寛史 志水秀郎 家串和真 林 真一郎  
林 真一郎
Original Articles (Selected)
  1. Iwashima Y, Fukuda T, Kusunoki H, Hayashi S, Kishida M, Yoshihara F, Nakamura S, Kamide K, Horio T, Kawano Y: Effects of percutaneous transluminal renal angioplasty on office and home blood pressure and home blood pressure variability in hypertensive patients with renal artery stenosis. HYPERTENSION. 2017; 69:109-117.
  2. Tawada M, Hayashi S, Ikegame Y, Nakashima S, Yoshida K: Possible involvement of tumor-producing VEGF-A in the recruitment of lymphatic endothelial progenitor cells from bone marrow. ONCOROL REP. 2014; 32:2359-2364.
  3. Doi Y, Iwashima Y, Yoshihara F, Kamide K, Hayashi S, Kubota Y, Nakamura S, Horio T, Kawano Y: Renal resistive index and cardiovascular and renal outcomes in essential hypertension. HYPERTENSION. 2012; 60:770-777.
  4. Tawada M, Hayashi S*, Osada S, Nakashima S, Yoshida K: Human gastric cancer organizes neighboring lymphatic vessels via recruitment of bone marrow-derived lymphatic endothelial progenitor cells. J GATROENTEROL. 2012; 47:1057-1060.
  5. Ikegame Y, Yamashita K, Hayashi S*, Mizuno H, Tawada M, You F, Yamada K, Tanaka Y, Egashira Y, Nakashima S, Yoshimura S, Iwama T: Comparison of mesenchymal stem cells from adipose tissue and bone marrow for ischemic stroke therapy. CYTOTHERAPY. 2011; 13:675-685.
  6. Hayashi S*, Sato N, Yamamoto A, Ikegame Y, Nakashima S, Ogihara T, Morishita R: Alzheimer disease-associated peptide, amyloid beta40 inhibits vascular regeneration with induction of endothelial autophagy. ARTERIOSCLER THROMB VASC BIOL. 2009; 29:1909-1915.
  7. Hayashi S*, Yamamoto A, You F, Yamashita K, Ikegame Y, Tawada M, Yoshimori T, Shimizu S, Nakashima S: The stent-eluting drugs sirolimus and paclitaxel suppress healing of the endothelium by induction of autophagy. AM J PATHOL. 2009;175:2226-2234.
  8. Masuda H, Kalka C, Takahashi T, Yoshida M, Wada M, Kobori M, Ito R, Iwaguro H, Eguchi M, Iwami Y, Tanaka R, Nakagawa Y, Sugimoto A, Ninomiya S, Hayashi SI, Kato S, Asahara T: Estrogen mediated endothelial progenitor cell biology and kinetics for physiological postnatal vasculogenesis. CIRC RES. 2007; 101:598-606.
  9. Hayashi S*, Asahara T, Masuda H, Isner JM, Losordo DW: Functional ephrin-B2 expression for promotive interaction between arterial and venous vessels in postnatal neovascularization. CIRCULATION. 2005; 111:2210-2218.
  10. Iwaguro H, Yamaguchi J, Kalka C, Murasawa S, Masuda H, Hayashi S, Silver M, Li T, Isner JM, Asahara T: Endothelial progenitor cell vascular endothelial growth factor gene transfer for vascular regeneration. CIRCULATION. 2002; 105:732-738.
  11. Suzuki T, Kopia G, Hayashi S, Bailey LR, Llanos G, Wilensky R, Klugherz BD, Papandreou G, Narayan P, Leon MB, Yeung AC, Tio F, Tsao PS, Falotico R, Carter AJ: Stent-based delivery of sirolimus reduced neointimal formation in a porcine coronary model. CIRCULATION. 2001; 104:1188-1193.
  12. Shin D, Garcia G, Hayashi SI, Gerety S, Asahara T, Stavrakis G, Isner J, Folkman J, Gimbrone MA, Anderson DJ: Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization. DEV BIOL. 2001; 230:139-150.
  13. Yamamoto K, Morishita R, Hayashi Si, Matsushita H, Nakagami H, Moriguchi A, Matsumoto K, Nakamura T, Kaneda Y, Ogihara T: Contribution of bcl-2, but not bcl-xl and bax, to antiapoptotic actions of hepatocyte growth factor in hypoxia-conditioned human endothelial cells. HYPERTENSION. 2001; 37:1341-1348.
  14. Kalka C, Masuda H, Takahashi T, Gordon R, Tepper O, Gravereaux E, Pieczek A, Iwaguro H, Hayashi SI, Isner JM, Asahara T: Vascular endothelial growth factor (165) gene transfer augments circulating endothelial progenitor cells in human subjects. CIRC RES. 2000; 86:1198-1202.
  15. Hayashi S, Morishita R, Matsushita H, Nakagami H, Taniyama Y, Nakamura T, Aoki M, Yamamoto K, Higaki J, Ogihara T: Cyclic AMP inhibited proliferation of human aortic vascular smooth muscle cells, accompanied by induction of p53 and p21. HYPERTENSION. 2000; 35:237-243.
  16. Morishita R, Nakamura S, Hayashi S, Taniyama Y, Moriguchi A, Nagano T, Taiji M, Noguchi H, Takeshita S, Matsumoto K, Nakamura T, Higaki J, Ogihara T: Therapeutic angiogenesis induced by human recombinant hepatocyte growth factor in rabbit hind limb ischemia model as cytokine supplement therapy. HYPERTENSION. 1999; 33:1379-1384.
  17. Hayashi S, Morishita R, Nakamura S, Yamamoto K, Moriguchi A, Nagano T, Taiji M, Noguchi H, Matsumoto K, Nakamura T, Higaki J, Ogihara T: Potential role of hepatocyte growth factor, a novel angiogenic growth factor, in peripheral arterial disease: downregulation of HGF in response to hypoxia in vascular cells. CIRCULATION. 1999; 100:II301-308.
  18. Hayashi SI, Morishita R, Aoki M, Moriguchi A, Kida I, Nakajima M, Kaneda Y, Higaki J, Ogihara T: In vivo transfer of gene and oligodeoxynucleotides into skin of fetal rats by incubation in amniotic fluid. GENE THER. 1996; 3:878-885.
Reviews (Selected)
  1. Klionsky DJ, Abdalla FC, Abeliovich H, Hayashi S et.al.: Guideline for the use and interpretation of assay for monitoring autophagy. AUTOPHAGY. 2012; 8:445-544.
  2. 林真一郎：血管構築のオーガナイザー： ephrin ligands-Eph receptor. 血管. 2002; 25:107-110.
  3. 浅原孝之、林真一郎：血管新生促進療法、血管研究の最前線 2000. 実験医学. 2000; 701-707.
青木元邦 勝谷友宏 里 直行 谷山義明 橋弥尚孝 日比野佐和子
東 純哉 牧野寛史 志水秀郎 家串和真 林 真一郎  
  Gリーダー 研究テーマ 主な論文
[共同研究グループ]
Page Top