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Home > Groups > Publications (Specially appointed researchers)

Groups

Specially appointed researchers group
  Leader Publications

Publications

Motokuni
Aoki		 Tomohiro
Katsuya		 Naoyuki
Sato		 Yoshiaki
Taniyama		 Naotaka
Hashiya		 Junya
Azuma
Hirofumi
Makino		 Hideo
Shimizu		 Kazuma
Iekushi		 Shin-ichiro
Hayashi		 Takashi
Miyake		 Katsutoshi
Tamura
Shin-ichiro Hayashi

Original Articles (Selected)

  1. Hayashi S*, Kawano Y, Morishita R, Kusano KF: Time-lagged amelioration of vascular endothelial function in malignant hypertension: different organs improved at different rates. LANCET. 2024; 403(10444):2630-2631. *Corresponding Author
  2. Iwashima Y, Kusunoki H, Taniyama A, Horio T, Hayashi SI, Kishida M, Fukuda T, Yoshihara F, Ishimitsu T, Kawano Y: Impact of percutaneous transluminal renal angioplasty on autonomic nervous system and natriuresis in hypertensive patients with renal artery stenosis. J AM HEART ASSOC. 2022; 11(6):e023655.
  3. Kusunoki H, Iwashima Y, Kawano Y, Hayashi SI, Kishida M, Horio T, Shinmura K, Yoshihara F. Circadian hemodynamics characteristics in hypertensive patients with primary aldosteronism. J HYPERTENS. 2018; 36(11):2260-2268.
  4. Iwashima Y, Fukuda T, Kusunoki H, Hayashi S, Kishida M, Yoshihara F, Nakamura S, Kamide K, Horio T, Kawano Y: Effects of percutaneous transluminal renal angioplasty on office and home blood pressure and home blood pressure variability in hypertensive patients with renal artery stenosis. HYPERTENSION. 2017; 69(1):109-117.
  5. Ohta Y, Kawano Y, Hayashi S, Iwashima Y, Yoshihara F, Nakamura S: Effects of cigarette smoking on ambulatory blood pressure, heart rate, and heart rate variability in treated hypertensive patients. CLIN EXP HYPERTENS. 2016; 38(6):510-513.
  6. Tawada M, Hayashi S*, Ikegame Y, Nakashima S, Yoshida K: Possible involvement of tumor-producing VEGF-A in the recruitment of lymphatic endothelial progenitor cells from bone marrow. ONCOROL REP. 2014; 32(6):2359-2364.
  7. Doi Y, Iwashima Y, Yoshihara F, Kamide K, Hayashi S, Kubota Y, Nakamura S, Horio T, Kawano Y: Renal resistive index and cardiovascular and renal outcomes in essential hypertension. HYPERTENSION. 2012; 60(3):770-777.
  8. Tawada M, Hayashi S*, Osada S, Nakashima S, Yoshida K: Human gastric cancer organizes neighboring lymphatic vessels via recruitment of bone marrow-derived lymphatic endothelial progenitor cells. J GATROENTEROL. 2012; 47(9):1057-1060.
  9. Ikegame Y, Yamashita K, Hayashi S*, Mizuno H, Tawada M, You F, Yamada K, Tanaka Y, Egashira Y, Nakashima S, Yoshimura S, Iwama T: Comparison of mesenchymal stem cells from adipose tissue and bone marrow for ischemic stroke therapy. CYTOTHERAPY. 2011; 13:675-685.
  10. Ikegame Y, Yamashita K, Hayashi S*, Yoshimura S, Nakashima S, Iwama T: Neutrophil elastase inhibitor prevents ischemic brain damage via reduction of vasogenic edema. HYPERTENS RES. 2010; 33(7):703-707.
  11. Hayashi S*, Sato N, Yamamoto A, Ikegame Y, Nakashima S, Ogihara T, Morishita R: Alzheimer disease-associated peptide, amyloid beta40 inhibits vascular regeneration with induction of endothelial autophagy. ARTERIOSCLER THROMB VASC BIOL. 2009; 29(11):1909-1915.
  12. Hayashi S*, Yamamoto A, You F, Yamashita K, Ikegame Y, Tawada M, Yoshimori T, Shimizu S, Nakashima S: The stent-eluting drugs sirolimus and paclitaxel suppress healing of the endothelium by induction of autophagy. AM J PATHOL. 2009; 175(5):2226-2234.
  13. Masuda H, Kalka C, Takahashi T, Yoshida M, Wada M, Kobori M, Ito R, Iwaguro H, Eguchi M, Iwami Y, Tanaka R, Nakagawa Y, Sugimoto A, Ninomiya S, Hayashi SI, Kato S, Asahara T: Estrogen mediated endothelial progenitor cell biology and kinetics for physiological postnatal vasculogenesis. CIRC RES. 2007; 101(6):598-606.
  14. Hayashi S*, Asahara T, Masuda H, Isner JM, Losordo DW: Functional ephrin-B2 expression for promotive interaction between arterial and venous vessels in postnatal neovascularization. CIRCULATION. 2005; 111(17):2210-2218.
  15. Iwaguro H, Yamaguchi J, Kalka C, Murasawa S, Masuda H, Hayashi S, Silver M, Li T, Isner JM, Asahara T: Endothelial progenitor cell vascular endothelial growth factor gene transfer for vascular regeneration. CIRCULATION. 2002; 105(6):732-738.
  16. Suzuki T, Kopia G, Hayashi S, Bailey LR, Llanos G, Wilensky R, Klugherz BD, Papandreou G, Narayan P, Leon MB, Yeung AC, Tio F, Tsao PS, Falotico R, Carter AJ: Stent-based delivery of sirolimus reduced neointimal formation in a porcine coronary model. CIRCULATION. 2001; 104(10):1188-1193.
  17. Shin D, Garcia G, Hayashi SI, Gerety S, Asahara T, Stavrakis G, Isner J, Folkman J, Gimbrone MA, Anderson DJ: Expression of ephrinB2 identifies a stable genetic difference between arterial and venous vascular smooth muscle as well as endothelial cells, and marks subsets of microvessels at sites of adult neovascularization. DEV BIOL. 2001; 230(2):139-150.
  18. Yamamoto K, Morishita R, Hayashi SI, Matsushita H, Nakagami H, Moriguchi A, Matsumoto K, Nakamura T, Kaneda Y, Ogihara T: Contribution of bcl-2, but not bcl-xl and bax, to antiapoptotic actions of hepatocyte growth factor in hypoxia-conditioned human endothelial cells. HYPERTENSION. 2001; 37(5):1341-1348.
  19. Kalka C, Masuda H, Takahashi T, Gordon R, Tepper O, Gravereaux E, Pieczek A, Iwaguro H, Hayashi SI, Isner JM, Asahara T: Vascular endothelial growth factor (165) gene transfer augments circulating endothelial progenitor cells in human subjects. CIRC RES. 2000; 86(12):1198-1202.
  20. Hayashi S, Morishita R, Matsushita H, Nakagami H, Taniyama Y, Nakamura T, Aoki M, Yamamoto K, Higaki J, Ogihara T: Cyclic AMP inhibited proliferation of human aortic vascular smooth muscle cells, accompanied by induction of p53 and p21. HYPERTENSION. 2000; 35(1 Pt 2):237-243.
  21. Morishita R, Nakamura S, Hayashi S, Taniyama Y, Moriguchi A, Nagano T, Taiji M, Noguchi H, Takeshita S, Matsumoto K, Nakamura T, Higaki J, Ogihara T: Therapeutic angiogenesis induced by human recombinant hepatocyte growth factor in rabbit hind limb ischemia model as cytokine supplement therapy. HYPERTENSION. 1999; 33(6):1379-1384.
  22. Hayashi S, Morishita R, Nakamura S, Yamamoto K, Moriguchi A, Nagano T, Taiji M, Noguchi H, Matsumoto K, Nakamura T, Higaki J, Ogihara T: Potential role of hepatocyte growth factor, a novel angiogenic growth factor, in peripheral arterial disease: downregulation of HGF in response to hypoxia in vascular cells. CIRCULATION. 1999;100(19 Suppl):II301-308.
  23. Hayashi SI, Morishita R, Aoki M, Moriguchi A, Kida I, Nakajima M, Kaneda Y, Higaki J, Ogihara T: In vivo transfer of gene and oligodeoxynucleotides into skin of fetal rats by incubation in amniotic fluid. GENE THER. 1996; 3(10):878-885.
  24. Hayashi S, Morishita R, Higaki J, Aoki M, Moriguchi A, Kida I, Sawa Y, Matsumoto K, Nakamura T, Kaneda Y, Ogihara T. BIOCHEM BIOPHYS RES COMMUN. 1996; 220(3):539-545.

Review (Selected)

  1. Sanada F, Hayashi S, Morishita R. Targeting the hallmarks of aging: mechanisms and therapeutic opportunities. FRONT CARDIOVASCULR MED. 2025;12:1631578.
  2. Hayashi SI*, Rakugi H, Morishita R. Insight into the role of angiopoietins in ageing-associated diseases. CELLS. 2020; 9(12):2636.
  3. Klionsky DJ, Abdalla FC, Abeliovich H,,, Hayashi S et.al.: Guideline for the use and interpretation of assay for monitoring autophagy. AUTOPHAGY. 2012; 8(4):445-544.
Motokuni
Aoki		 Tomohiro
Katsuya		 Naoyuki
Sato		 Yoshiaki
Taniyama		 Naotaka
Hashiya		 Junya
Azuma
Hirofumi
Makino		 Hideo
Shimizu		 Kazuma
Iekushi		 Shin-ichiro
Hayashi		 Takashi
Miyake		 Katsutoshi
Tamura
  Leader Publications
[Specially appointed researchers group]
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